Characterization of myenteric sensory neurons in the mouse small intestine.

Intrinsic sensory neurons of mouse gut – towards a detailed knowledge of enteric neural circuitry across species. Focus on “Characterization of myenteric sensory neurons in the mouse small intestine”

Intrinsic sensory neurons of mouse gut--toward a detailed knowledge of enteric neural circuitry across species. Focus on "characterization of myenteric sensory neurons in the mouse small intestine".

The enteric nervous system of the gut is largely self-contained and includes intrinsic sensory (or primary afferent) neurons, a variety of interneurons and several classes of motor neurons (Bornstein et al. 2002; Furness et al. 2004a). Detailed studies of guinea pig ileum have identified all of these neurons and allowed construction of a model neural circuit that accounts for some intestinal be...

Birthdating of myenteric neuron subtypes in the small intestine of the mouse.

There are many different types of enteric neurons. Previous studies have identified the time at which some enteric neuron subtypes are born (exit the cell cycle) in the mouse, but the birthdates of some major enteric neuron subtypes are still incompletely characterized or unknown. We combined 5-ethynynl-2'-deoxyuridine (EdU) labeling with antibody markers that identify myenteric neuron subtypes...

Mechanosensitive Enteric Neurons in the Myenteric Plexus of the Mouse Intestine

BACKGROUND Within the gut the autonomous enteric nervous system (ENS) is able to sense mechanical stimuli and to trigger gut reflex behaviour. We previously proposed a novel sensory circuit in the ENS which consists of multifunctional rapidly adapting mechanosensitive enteric neurons (RAMEN) in the guinea pig. The aim of this study was to validate this concept by studying its applicability to o...

Pattern of distribution and co-localization of NOS and ATP in the myenteric plexus of human fetal stomach and intestine.

The pattern of distribution and co-localization of nitric oxide synthase (NOS) and quinacrine fluorescence (indicative of vesicular adenosine 5'-triphosphate, ATP), and co-localization of NADPH-diaphorase (NADPH-d) activity and NOS-immunoreactivity in the myenteric plexus of pre-term human fetal (6-17 weeks of gestation) stomach and small intestine was examined using immunohistochemical and his...